Enhancing nutritional niche and host defenses by modifying the gut microbiome.
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ABSTRACT:
SUBMITTER: Sun Q
PROVIDER: S-EPMC9664710 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Publications
Enhancing nutritional niche and host defenses by modifying the gut microbiome.
Sun Qing Q Vega Nic M NM Cervantes Bernardo B Mancuso Christopher P CP Mao Ning N Taylor Megan N MN Collins James J JJ Khalil Ahmad S AS Gore Jeff J Lu Timothy K TK
Molecular systems biology 20221101 11
The gut microbiome is essential for processing complex food compounds and synthesizing nutrients that the host cannot digest or produce, respectively. New model systems are needed to study how the metabolic capacity provided by the gut microbiome impacts the nutritional status of the host, and to explore possibilities for altering host metabolic capacity via the microbiome. Here, we colonized the nematode Caenorhabditis elegans gut with cellulolytic bacteria that enabled C. elegans to utilize ce ...[more]
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