Ontology highlight
ABSTRACT:
SUBMITTER: Ogata N
PROVIDER: S-EPMC9668052 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Journal of bioinformatics and systems biology : Open access 20221007 4
Tissue culture environment liberate cells from ordinary laws of multi-cellular organisms. This liberation enables cells several behaviors, such as growth, dedifferentiation, acquisition of pluripotency, immortalization and reprogramming. Each phenomenon is relating to each other and hardly to determine. Recently, dedifferentiation of animal cell was quantified as increasing liberality which is information entropy of transcriptome. The increasing liberality induced by tissue culture may reappear ...[more]