Shape Fidelity Evaluation of Alginate-Based Hydrogels through Extrusion-Based Bioprinting.

ABSTRACT: Extrusion-based 3D bioprinting is a promising technique for fabricating multi-layered, complex biostructures, as it enables multi-material dispersion of bioinks with a straightforward procedure (particularly for users with limited additive manufacturing skills). Nonetheless, this method faces challenges in retaining the shape fidelity of the 3D-bioprinted structure, i.e., the collapse of filament (bioink) due to gravity and/or spreading of the bioink owing to the low viscosity, ultimately complicating the fabrication of multi-layered designs that can maintain the desired pore structure. While low viscosity is required to ensure a continuous flow of material (without clogging), a bioink should be viscous enough to retain its shape post-printing, highlighting the importance of bioink propert

SUBMITTER: Temirel M 

PROVIDER: S-EPMC9680455 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature