A scoping review of pediatric microdialysis: A missed opportunity for microdialysis in the pediatric neuro-oncology setting.

ABSTRACT:

Background

Brain microdialysis is a minimally invasive technique for monitoring analytes, metabolites, drugs, neurotransmitters, and/or cytokines. Studies to date have centered on adults with traumatic brain injury, with a limited number of pediatric studies performed. This scoping review details past use of brain microdialysis in children and identifies potential use for future neuro-oncology trials.

Methods

In December 2020, Cochrane Library: CENTRAL, Embase, PubMed, Scopus, and Web of Science: Core Collection were searched. Two reviewers screened all articles by title and abstract review and then full study texts, using microdialysis in patients less than 18 yo.

Results

Of the 1171 articles screened, 49 were included. The 49 studies included 472 pediatric patients

SUBMITTER: Dalmage MR 

PROVIDER: S-EPMC9683385 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature