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Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections.

ABSTRACT: Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.

SUBMITTER: Pedersen RM 

PROVIDER: S-EPMC9707601 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections.

Pedersen Rune M RM   Bang Line L LL   Tornby Ditte S DS   Madsen Lone W LW   Holm Dorte K DK   Sydenham Thomas V TV   Johansen Isik S IS   Jensen Thøger G TG   Justesen Ulrik S US   Andersen Thomas E TE  

Emerging infectious diseases 20221108 12

Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone. ...[more]

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