Hemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study.

ABSTRACT:

Objectives

We aimed to describe the variation of hemostasis proteins in children with bacterial infections due to different pathogens ( Neisseria meningitidis, Streptococcus pneumoniae, Staphylococcus aureus , and group A streptococcus [GAS]) and to study hemostasis proteins in relation to mortality.

Design

Preplanned analysis in prospective cohort study.

Setting

Hospitals in five European countries (Austria, The Netherlands, Spain, Switzerland, and the United Kingdom).

Patients

Admitted children (2012-2016) with community-acquired infections due to meningococci ( n = 83), pneumococci ( n = 64), S. aureus (n = 50), and GAS ( n = 44) with available serum samples collected less than 48 hours after admission.

Interventions

None.

Measurements and main res

SUBMITTER: Hagedoorn NN 

PROVIDER: S-EPMC9708080 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature