Impaired renal function and mortalities in acute heart failure with different phenotypes.

ABSTRACT:

Aims

Impaired renal function (IRF) prevails in patients with acute heart failure. The study aimed to investigate the prevalence of on-admission IRF and its association with short-term and long-term mortalities in patients hospitalized for HF with reduced (HFrEF), mildly reduced (HFmrEF), and preserved (HFpEF) left ventricular ejection fraction (LVEF).

Methods

Patients hospitalized for acute heart failure were enrolled and stratified by LVEF into three phenotypes as HFpEF (≥50%), HFmrEF (40-49%), and HFrEF (<40%). IRF was defined as an estimated glomerular filtration rate of ≤60 mL/min/1.73m² on admission. National Death Registry was linked for the identification of mortality.

Results

Of 2613 patients enrolled, 673 (25.7%) had HFrEF, 367 (14.0%) had HFmrEF,

SUBMITTER: Huang WM 

PROVIDER: S-EPMC9715785 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature