A cohort study of intrapartum group B streptococcus prophylaxis on atopic dermatitis in 2-year-old children.

ABSTRACT:

Objective

To understand the occurrence of atopic dermatitis (AD) in children aged 2 years on exposure to maternal group B streptococcus (GBS) antibiotic prophylaxis (IAP).

Design

Retrospective cohort study of 2909 mother-child pairs.

Setting

Taixing People's Hospital in Eastern China.

Participants

Term infants born 2018-2019, followed longitudinally from birth to 2 years.

Exposures

The GBS-IAP was defined as therapy with intravenous penicillin G or ampicillin or cefazolin ≥ 4 h prior to delivery to the mother. Reference infants were defined as born without or with other intrapartum antibiotic exposure.

Outcomes

The logistic regression models were employed to analyze the effect of intrapartum GBS prophylaxis on AD in 2-year-old children during deli

SUBMITTER: Hong Z 

PROVIDER: S-EPMC9716662 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature