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ABSTRACT: Background
While point-of-care ultrasound (POCUS) has been used to track worsening COVID-19 disease it is unclear if there are dynamic differences between severity trajectories.Methods
We studied 12-lung zone protocol scans from 244 participants [with repeat scans obtained in 3 days (N = 114), 7 days (N = 53), and weekly (N = 9)] ≥ 18 years of age hospitalized for COVID-19 pneumonia. Differences in mean lung ultrasound (LUS) scores and percent of lung fields with A-lines over time were compared between peak severity levels (as defined by the WHO clinical progression scale) using linear mixed-effects models.Results
Mean LUS scores were elevated by 0.19 (p = 0.035) and A-lines were present in 14.7% fewer lung fields (p = 0.02) among those with ICU-level or fatal peak illness compared to less severe hospitalized illness, regardless of duration of illness. There were no differences between severity groups in the trajectories of mean LUS score 0.19 (p = 0.66) or percent A-lines (p = 0.40).Discussion
Our results do not support the use of serial LUS scans to monitor COVID-19 disease progression among hospitalized adults.
SUBMITTER: Blair PW
PROVIDER: S-EPMC9720255 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Blair Paul W PW Hwang Jimin J Pearce Jackson J Fong Tiffany C TC Cui Erjia E Herrera Phabiola P Liu Gigi G Crainiceanu Ciprian C Siddharthan Trishul T Clark Danielle V DV
Frontiers in medicine 20221121
<h4>Background</h4>While point-of-care ultrasound (POCUS) has been used to track worsening COVID-19 disease it is unclear if there are dynamic differences between severity trajectories.<h4>Methods</h4>We studied 12-lung zone protocol scans from 244 participants [with repeat scans obtained in 3 days (<i>N</i> = 114), 7 days (<i>N</i> = 53), and weekly (<i>N</i> = 9)] ≥ 18 years of age hospitalized for COVID-19 pneumonia. Differences in mean lung ultrasound (LUS) scores and percent of lung fields ...[more]