Temporal profiles of systolic blood pressure variability and neurologic outcomes after endovascular thrombectomy.

ABSTRACT:

Introduction

Observational studies have found an increased risk of hemorrhagic transformation and worse functional outcomes in patients with higher systolic blood pressure variability (BPV). However, the time-varying behavior of BPV after endovascular thrombectomy (EVT) and its effects on functional outcome have not been well characterized.

Patients and methods

We analyzed data from an international cohort of patients with large-vessel occlusion stroke who underwent EVT at 11 centers across North America, Europe, and Asia. Repeated time-stamped blood pressure data were recorded for the first 72 h after thrombectomy. Parameters of BPV were calculated in 12-h epochs using five established methodologies. Systolic BPV trajectories were generated using group-based trajectory mode

SUBMITTER: Prasad A 

PROVIDER: S-EPMC9720854 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature