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Case report: Pragmatic impairment in multiple sclerosis after worsening of clinical symptoms.

ABSTRACT: Pragmatics, defined as the ability to integrate language and context to communicate effectively, may be impaired in Multiple Sclerosis (MS). We present the case of a patient with active secondary progressive MS who, after a first neuropsychological assessment that evidenced only a slight pragmatic impairment, suffered a sudden worsening of her clinical conditions, treated with corticosteroids. After this clinical worsening, her pragmatic abilities declined markedly, both in comprehension and production. This worsening was accompanied by a decline only in one attention task, in the context of an overall stable cognitive functioning. We conclude that pragmatics may be a domain particularly susceptible to cognitive worsening, highlighting the importance of its assessment in clinical practice.

SUBMITTER: Lago S

PROVIDER: S-EPMC9731094 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Case report: Pragmatic impairment in multiple sclerosis after worsening of clinical symptoms.

Lago Sara S Bevilacqua Francesca F Stabile Maria Rosaria MR Scarpazza Cristina C Bambini Valentina V Arcara Giorgio G

Frontiers in psychology 20221124

Pragmatics, defined as the ability to integrate language and context to communicate effectively, may be impaired in Multiple Sclerosis (MS). We present the case of a patient with active secondary progressive MS who, after a first neuropsychological assessment that evidenced only a slight pragmatic impairment, suffered a sudden worsening of her clinical conditions, treated with corticosteroids. After this clinical worsening, her pragmatic abilities declined markedly, both in comprehension and pro ...[more]

PMID: 36506966

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