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Asbestos Exposure and Severity of COVID-19.


ABSTRACT:

Background

The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection.

Methods

We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were collected during admission. After discharge, a previously validated occupational exposure to asbestos questionnaire was administered. Spirometry, CO diffusion test, the 6-min walk test, and high-resolution chest CT were performed. Patients who required respiratory support (oxygen, CPAP, or NIV) were considered severe.

Results

In total, 293 patients (mean age 54 + 13 years) were included. Occupational exposure to asbestos was detected in 67 (24%). Patients with occupational exposure to asbestos had a higher frequency of COVID-19 pneumonia requiring respiratory support (n = 52, 77.6%) than their unexposed peers (n = 139, 61.5%) (p = 0.015). Asbestos exposure was associated with COVID-19 severity in the univariate but not in the multivariate analysis. No differences were found regarding follow-up variables including spirometry and the DLCO diffusion, the 6-min walk test, and CT alterations.

Conclusions

In hospitalised patients with COVID-19 pneumonia, those with occupational exposure to asbestos more frequently needed respiratory support. However, an independent association between asbestos exposure and COVID-19 severity could not be confirmed.

SUBMITTER: Granados G 

PROVIDER: S-EPMC9739528 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Publications

Asbestos Exposure and Severity of COVID-19.

Granados Galo G   Sáez-López María M   Aljama Cristina C   Sampol Júlia J   Cruz María-Jesús MJ   Ferrer Jaume J   Se-Covid-Team  

International journal of environmental research and public health 20221206 23


<h4>Background</h4>The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection.<h4>Methods</h4>We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were collected during admission. After discharge, a previously validated occupational exposure to asbestos questionnaire was administered. Spirometry, CO diffusion test, the 6-min walk test, and hi  ...[more]

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