Organocatalyst based cross-catalytic system.

ABSTRACT: We present our design of a cross-catalytic system based on organocatalysis. The system features two organic reactions, namely a deprotection reaction of Fmoc protected proline and a Mannich reaction between acetone and dihydroisoquinoline. The products of these two reactions, proline and a tetrahydroisoquinoline, respectively, are capable of reciprocal reaction rate enhancement. Detailed kinetic studies of the system and seeding experiments support the cross-catalytic relationship in the reaction network.

SUBMITTER: Veenstra MJ 

PROVIDER: S-EPMC9753097 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature