Kidney function, cardiovascular outcomes and survival of living kidney donors with hypertension: a systematic review protocol

ABSTRACT:

Introduction

Hypertension has been considered a contraindication for living kidney donation in the past. Since transplantation from living kidney donors remains the best modality for kidney failure, there is now an increased acceptance of living kidney donors with hypertension. However, the safety of this practice for the cardiovascular and kidney health of the donor is unclear. We will conduct a systematic review to summarise and synthesise the existing literature on this topic.

Methods and analysis

A systematic review of prospective randomised and non-randomised and retrospective studies will be conducted. MEDLINE, EMBASE, Cochrane CENTRAL and EBM reviews published from January 1946 to December 2021 will be reviewed. Primary outcome will be the difference in the surviva

SUBMITTER: Bugeja A 

PROVIDER: S-EPMC9756152 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature