Virological failure among people living with HIV receiving second-line antiretroviral therapy in Pune, India.

ABSTRACT:

Background

The number of people receiving second-line antiretroviral therapy (ART) has increased as global access to ART has expanded. Data on the burden and factors associated with second-line ART virologic failure (VF) from India remain limited.

Methods

We conducted cross-sectional viral load (VL) testing among adults (≥ 18 years) who were registered at a publicly funded ART center in western India between 2014 and 2015 and had received second-line ART for at least 6 months. Sociodemographic and clinical characteristics were abstracted from routinely collected programmatic data. Logistic regression evaluated factors associated with VF (defined as VL > 1000 copies/mL).

Results

Among 400 participants, median age was 40 years (IQR 34-44), 71% (285/400) were male, and 1

SUBMITTER: Salvi S 

PROVIDER: S-EPMC9758821 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature