Short sleep duration and the risk of nonalcoholic fatty liver disease/metabolic associated fatty liver disease: a systematic review and meta-analysis.

ABSTRACT:

Purpose

It is unclear whether or not nonalcoholic fatty liver disease (NAFLD)/metabolic dysfunction-associated fatty liver disease (MAFLD) is related to short sleep duration. A meta-analysis was conducted to determine if inadequate sleep time increased the risk of NAFLD/MAFLD.

Methods

A comprehensive systematic literature review was conducted in the Embase, PubMed, and Cochrane Library databases from inception to August 1, 2022. Studies examining the correlation between inadequate sleep time and the risk of NAFLD/MAFLD were included. We pooled the odds ratios (ORs) and 95% confidence intervals (CIs) using a random-effects model.

Results

This meta-analysis included fifteen studies involving a total of 261,554 participants. In the pooled analysis, short sleep duration w

SUBMITTER: Yang J 

PROVIDER: S-EPMC9771780 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature