Chronic mechanical trauma/irritation and oral carcinoma: A systematic review showing low evidence to support an association.

ABSTRACT:

Background

Chronic trauma of oral mucosa, resulting from repeated and persistent mechanical irritative action of an intraoral injury agent, has repeatedly been reported to be possibly implicated in the development of oral squamous cell carcinoma (OSCC).

Objectives

The present systematic review aimed to assess whether chronic mechanical trauma can be considered a risk factor for OSCC.

Data sources

PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), Scopus; EMBASE, Web of Science.

Study eligibility criteria

Cohort studies comparing OSCC incidence among subjects with/without chronic mechanical trauma or case-control or cross-sectional studies comparing chronic mechanical trauma among subjects with/without OSCC.

Results

Only one prospective cas

SUBMITTER: Pentenero M 

PROVIDER: S-EPMC9787889 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature