Physical activity and risk of all-cause mortality in patients with stable angina pectoris: Effect modification by β-blocker treatment.

ABSTRACT:

Background

Physical activity (PA) influences sympathetic stimulation, platelet activation as well as vascular function, and has been associated with improved health outcomes in patients with coronary heart disease. β-blocker therapy reduces sympathetic activity and improves platelet and endothelial function. We investigated if β-blocker treatment modifies the association of self-reported PA with the risk of all-cause mortality.

Methods

A total of 2284 patients undergoing elective coronary angiography for suspected stable angina pectoris (SAP) were studied. Using Cox modeling, we examined associations between PA (categorized as 'sedentary/inactive', 'low', 'moderate', and 'high') and all-cause mortality according to β-blocker therapy.

Results

During a median follow-up

SUBMITTER: Dhar I 

PROVIDER: S-EPMC9789355 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature