Association Between Parkinson's Disease and Coronary Artery Disease: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The relationship between Parkinson's disease (PD) and coronary artery disease (CAD) is unclear.

Objective

This study aims to investigate whether PD and CAD are associated through systematic review and meta-analysis of observational studies.

Methods

Electronic database search of PubMed, EMBASE, and Web of Science for observational studies published from 1 January 2010 to 1 August 2021 was conducted using terms related to PD and CAD. Unadjusted risk ratios (RR) and odds ratios (OR) of included cohort and case-control studies respectively were used to ascertain the association between PD and CAD. Study heterogeneity was evaluated using the I2 test.

Results

Forty-one full-text studies were initially retrieved for eligibility assessment. Five studies that

SUBMITTER: Chua SKK 

PROVIDER: S-EPMC9789484 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature