Transplantation of small ovarian tissue fragments using pipelle device is effective: method evaluation and reproductive outcomes.

ABSTRACT:

Purpose

To assess the feasibility, effectiveness, and reproductive outcomes of transplantation of tiny cryopreserved ovarian pieces through a pipelle cannula during laparoscopic surgery.

Methods

A retrospective study of patients who underwent ovarian tissue transplantation for fertility restoration between 2004 and 2022. The "pipelle group" had their ovarian cortex cut into tiny pieces of ~ 1-2 mm³ before cryopreservation. The pieces were too small to be handled and transplanted via standard laparoscopic tools. Transplantation was performed using a pipelle cannula during laparoscopic surgery. The "control group" underwent transplants of ovarian cortex pieces 1-2 mm thick, measuring approximately 25-50 mm² pieces, using standard procedures.

Results

SUBMITTER: Safrai M 

PROVIDER: S-EPMC9790840 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature