Breast cancer combined prognostic model based on lactate metabolism genes.
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ABSTRACT:
SUBMITTER: Lu N
PROVIDER: S-EPMC9794285 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
Breast cancer combined prognostic model based on lactate metabolism genes.
Lu Na N Guan Xiao X Bao Wei W Fan Zongyao Z Zhang Jianping J
Medicine 20221201 51
To investigate the impact of lactate metabolism genes, lactate metabolism-related genes (LMRG), and immune infiltrating cells on the prognosis of breast cancer. LMRG was identified via single-cell sequencing. Immune cell infiltration was obtained by the CIBERSORT method. The prognostic genes were chosen by cox regression and the least absolute selection operator approach. lactate metabolism-associated immune-infiltrating cells was determined by difference analysis. The GSE20685 dataset was used ...[more]
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