Genome-wide association study reveals the genetic determinism of serum biochemical indicators in ducks.

ABSTRACT:

Background

The serum is rich in nutrients and plays an essential role in electrolyte and acid-base balance, maintaining cellular homeostasis. In addition, serum parameters have been commonly used as essential biomarkers for clinical diagnosis. However, little is known about the genetic mechanism of the serum parameters in ducks.

Results

This study measured 18 serum parameters in 320 samples of the F₂ segregating population generated by Mallard × Pekin duck. The phenotypic correlations showed a high correlation between LDH, HBDH, AST, and ALT (0.59-0.99), and higher coefficients were also observed among TP, ALB, HDL-C, and CHO (0.46-0.87). And then, we performed the GWAS to reveal the genetic basis of the 18 serum biochemical parameters in ducks. Fourteen candidate

SUBMITTER: Tang H 

PROVIDER: S-EPMC9795613 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature