Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: Methodology and applications.

ABSTRACT:

Background

The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible treatment of childhood pneumonia for the improvement of current pneumonia case management guidelines.

Methods

Using data from a published systematic review and expert knowledge, we identified studies meeting our eligibility criteria and invited investigators to share individual-level patient data. We collected data on demographic informat

SUBMITTER: Martin H 

PROVIDER: S-EPMC9798037 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature