Association between oxidative balance score and new-onset hypertension in adults: A community-based prospective cohort study.

ABSTRACT:

Introduction

Oxidative stress plays a key role in the pathophysiology of hypertension development. The oxidative balance score (OBS) comprises dietary and lifestyle pro- and anti-oxidant components and reflects the overall oxidative stress burden. We aimed to evaluate the association between the OBS and new-onset hypertension (HTN) using large, community-based, prospective Korean cohort data.

Methods

Among 10,030 participants aged 40-69 years included in the Korean Genome and Epidemiology Study, the data of 5,181 participants were analyzed. The hazard ratio (HR) and 95% confidence interval (CI) for new-onset HTN according to sex-specific OBS quartile groups were calculated using univariable and multivariable Cox proportional hazard regression analyses.

Results

During

SUBMITTER: Lee JH 

PROVIDER: S-EPMC9798298 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature