Artifact suppression in readout-segmented consistent K-t space EPSI (RS-COKE) for fast ¹ H spectroscopic imaging at 7 T.

ABSTRACT:

Purpose

Fast proton (¹ H) MRSI is an important diagnostic tool for clinical investigations, providing metabolic and spatial information. MRSI at 7 T benefits from increased SNR and improved separation of peaks but requires larger spectral widths. RS-COKE (Readout-Segmented Consistent K-t space Epsi) is an echo planar spectroscopic imaging (Epsi) variant capable to support the spectral width required for human brain metabolites spectra at 7 T. However, mismatches between readout segments lead to artifacts, particularly when subcutaneous lipid signals are not suppressed. In this study, these mismatches and their effects are analyzed and reduced.

Methods

The following corrections to the data were performed: i) frequency-dependent phase corrections; ii) k-space trajec

SUBMITTER: Seginer A 

PROVIDER: S-EPMC9804880 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature