Disease activity in patients with immune-mediated inflammatory diseases after SARS-CoV-2 vaccinations.

ABSTRACT: For patients with immune-mediated inflammatory diseases (IMIDs), concerns exist about increased disease activity after vaccination. We aimed to assess changes in disease activity after SARS-CoV-2 vaccination in patients with IMIDs, and determine risk factors for increased disease activity. In this substudy of a prospective observational cohort study (Target-to-B!), we included patients with IMIDs who received a SARS-CoV-2 vaccine. Patients reported changes in disease activity on a five-point Likert scale every 60 days for up to twelve months after first vaccination. In case of self-reported increased activity, hospital records were screened whether the treating physician reported increased activity, and for potential intensification of immunosuppressive (ISP) treatment. Mixed models were u

SUBMITTER: van Dam KPJ 

PROVIDER: S-EPMC9805902 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature