Age-specific contribution of contacts to transmission of SARS-CoV-2 in Germany.

ABSTRACT: Current estimates of pandemic SARS-CoV-2 spread in Germany using infectious disease models often do not use age-specific infection parameters and are not always based on age-specific contact matrices of the population. They also do usually not include setting- or pandemic phase-based information from epidemiological studies of reported cases and do not account for age-specific underdetection of reported cases. Here, we report likely pandemic spread using an age-structured model to understand the age- and setting-specific contribution of contacts to transmission during different phases of the COVID-19 pandemic in Germany. We developed a deterministic SEIRS model using a pre-pandemic contact matrix. The model was optimized to fit age-specific SARS-CoV-2 incidences reported by the German Nati

SUBMITTER: Rodiah I 

PROVIDER: S-EPMC9807433 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature