Ultrafast excited state dynamics and light-switching of [Ru(phen)₂(dppz)]²⁺ in G-quadruplex DNA.

ABSTRACT: The triplet metal to ligand charge transfer (³MLCT) luminescence of ruthenium (II) polypyridyl complexes offers attractive imaging properties, specifically towards the development of sensitive and structure-specific DNA probes. However, rapidly-deactivating dark state formation may compete with ³MLCT luminescence depending on different DNA structures. In this work, by combining femtosecond and nanosecond pump-probe spectroscopy, the ³MLCT relaxation dynamics of [Ru(phen)₂(dppz)]²⁺ (phen = 1,10-phenanthroline, dppz = dipyridophenazine) in two iconic G-quadruplexes has been scrutinized. The binding modes of stacking of dppz ligand on the terminal G-quartet fully and partially are clearly identified based on the biexponential decay dynami

SUBMITTER: Yang C 

PROVIDER: S-EPMC9814642 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature