Long-term fatigue following aneurysmal subarachnoid haemorrhage and the impact on employment.

ABSTRACT:

Background and purpose

Fatigue is common following aneurysmal subarachnoid haemorrhage (aSAH) but little is known about its frequency, prognosis and impact on employment. The aim of this study was to assess the frequency of fatigue, whether it changes over time and the relationship to employment in the long term.

Methods

This was a retrospective observational study of aSAH cases and matched controls from the UK Biobank. The presence of fatigue was compared between cases and controls using the chi-squared test. The change in frequency over time was assessed using Spearman's rank correlation coefficient. The effect of fatigue on employment was assessed using mediation analysis.

Results

Fatigue is more common following aSAH compared to matched controls (aSAH 18.7%; contr

SUBMITTER: Gaastra B 

PROVIDER: S-EPMC9825863 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature