Comorbidities in patients with Unverricht-Lundborg disease (EPM1).

ABSTRACT:

Background

Unverricht-Lundborg disease (EPM1) typically leads to accumulating disability. Disability may also be caused by comorbidities but there are no data available on these.

Aims of the study

To investigate the frequency of comorbidities in EPM1.

Methods

Comorbidity data of a previously described cohort of 135 Finnish patients with EPM1 were retrieved from neurological, surgical (including subspecialities), internal medicine (including subspecialities) and intensive care patient charts of the treating hospitals.

Results

Mean follow-up time was 31.4 years (SD 12.4 years, range 6.8-57.8 years), during which at least one comorbidity was observed in 107 patients (79%) and three or more in 53 (39%). The most common diagnostic categories were external injuries,

SUBMITTER: Sipila JOT 

PROVIDER: S-EPMC9826374 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature