Outcomes of patients with esophageal cancer after allogeneic hematopoietic stem cell transplantation

ABSTRACT:

Background

The improving survival in patients after allogeneic hematopoietic stem cell transplantation (aHCT) has warranted an increased attention to the long-term complications after aHCT especially second malignancies. The risk of developing esophageal cancer is thought to be higher than other malignancies after aHCT. There are limited data on the clinical characteristics, staging, treatment options and outcomes in these patients.

Methods

We retrospectively reviewed all patients who underwent aHCT at our centre over 30 years and identified patients who developed secondary esophageal cancer. Patients were analyzed for transplant details, disease characteristics and therapy, relapse free survival (RFS), and overall survival (OS).

Results

Ten patients [females 40%

SUBMITTER: Vasudevan Nampoothiri R 

PROVIDER: S-EPMC9830323 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature