Association between Helicobacter pylori infection and carotid atherosclerosis in Chinese adults.

ABSTRACT:

Background and aims

The role of Helicobacter pylori (H. pylori) infection in carotid atherosclerosis remains inconsistent and sometimes controversial. We aimed to determine whether H. pylori infection is associated with carotid atherosclerotic plaques in a large number of Chinese adults.

Methods

We recruited 108,210 Chinese adults who participated in a standard medical screening with both carotid ultrasonic examination and ¹³C-urea breath test for H.pylori infection from two Chinese cohorts. A total of 93,915 adults were included in the analysis after excluding participants with cardiovascular disease (CVD) and carotid plaques at baseline. Hazard ratio (HR) for developing carotid plaques by H. pylori infection was analyzed using

SUBMITTER: Du L 

PROVIDER: S-EPMC9833265 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature