Retrospective analysis of sepsis in cutaneous T-cell lymphoma reveals significantly greater risk in Black patients.

ABSTRACT:

Background

Sepsis is a leading cause of morbidity, mortality, and resource utilization among patients with cutaneous T-cell lymphoma (CTCL).

Objective

To characterize the demographic, clinical, and microbial attributes distinguishing patients with CTCL sepsis from other patients with non-Hodgkin lymphoma (NHL) sepsis and patients with CTCL in general.

Methods

Two-part retrospective cohort study at an academic medical center from 2001-2019 involving patients with CTCL (n = 97) and non-CTCL NHL (n = 88) admitted with sepsis, and a same-institution CTCL patient database (n = 1094). Overall survival was estimated by Kaplan-Meier analyses.

Results

Patients with CTCL sepsis were more likely to be older, Black, experience more sepsis episodes, die or be readmitted wit

SUBMITTER: Hooper MJ 

PROVIDER: S-EPMC9839541 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature