Gut microbiota and microbiota-based therapies for Clostridioides difficile infection.
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ABSTRACT:
SUBMITTER: Chopra T
PROVIDER: S-EPMC9868170 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Gut microbiota and microbiota-based therapies for <i>Clostridioides difficile</i> infection.
Chopra Teena T Hecht Gail G Tillotson Glenn G
Frontiers in medicine 20230109
<i>Clostridioides difficile</i> infection poses significant clinical challenges due to its recurrent nature. Current antibiotic management does not address the underlying issue, that of a disturbed gastrointestinal microbiome, called dysbiosis. This provides a supportive environment for the germination of <i>C. difficile</i> spores which lead to infection and toxin production as well as an array of other health conditions. The use of microbiome restoration therapies such as live biotherapeutics ...[more]
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