Beta-glucans induce cellular immune training and changes in intestinal morphology in poultry.

ABSTRACT:

Introduction

Beta-glucans are known as biological response modifiers due to their ability to activate the immune system. This research aimed to determine the efficacy and safety of feeding beta-glucans from various sources on the immune status and intestinal morphology of chickens.

Methods

To this end we used in vitro and in vivo set-ups. In the in vitro set-up the chicken macrophage cell line HD-11 was used to measure the response of the chicken immune cells to beta-glucans extracted from algae and mushrooms on immune-related gene expression and associated activities. Additionally, we conducted two in vivo experiments using either beta-glucans extracted from yeast or mix of yeast and mushrooms beta-glucans as part of the chicks feed in order to t

SUBMITTER: Bar-Dagan H 

PROVIDER: S-EPMC9868956 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature