Discovery of endogenous nitroxyl as a new redox player in Arabidopsis thaliana.

ABSTRACT: Nitroxyl (HNO) is the one-electron reduced and protonated congener of nitric oxide (•NO), owning a distinct chemical profile. Based on real-time detection, we demonstrate that HNO is endogenously formed in Arabidopsis. Senescence and hypoxia induce shifts in the redox balance, triggering HNO decay or formation mediated by non-enzymatic •NO/HNO interconversion with cellular reductants. The stimuli-dependent HNO generation supports or competes with •NO signalling, depending on the local redox environment.

SUBMITTER: Arasimowicz-Jelonek M 

PROVIDER: S-EPMC9873566 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature