Dataset Information

Diabetes mellitus and the risk of post-acute COVID-19 hospitalizations-a nationwide cohort study.

ABSTRACT:

Aims

This cohort study, based on Danish health registers, examined the post-acute consequences of hospitalization for COVID-19 in patients with diabetes.

Methods

The study population comprised all Danish citizens (≥18 years old) who had diabetes when the pandemic started. A patient was exposed if he/she had a hospitalization with COVID-19 after 1 March 2020. A patient was unexposed when he/she was not hospitalized with COVID-19 between 1 March 2020 and the end of follow-up (4 January 2022), or the first registered event of interest. The outcomes included post-COVID-19 hospitalizations and death. We used a Cox proportional hazards model with time varying exposure estimating the hazards ratio (HR) to analyze if the hazard for an outcome of interest was impacted by being hospitalized with COVID-19.

Results

In patients with type 1 diabetes, 101 were hospitalized with COVID-19, and 25,459 were not. We did not have sufficient statistical power to identify differences in risk for those with type 1 diabetes. In type 2 diabetes, 1515 were hospitalized with COVID-19, and 95,887 were not. The adjusted HRs of post-acute hospitalization for respiratory diseases and infections were 1.71 (95% CI 1.45-2.03) and 1.87 (95% CI 1.61-2.18), respectively. The HR of death was 2.05 (95% CI 1.73-2.43). Patients with uncertain type had results similar to those with type 2 diabetes.

Conclusions/interpretation

In type 2 diabetes and diabetes of uncertain type, hospitalization with COVID-19 was associated with an increased risk of post-acute hospitalization for respiratory diseases, infections and death.

SUBMITTER: Norgard BM

PROVIDER: S-EPMC9874838 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Publications

Diabetes mellitus and the risk of post-acute COVID-19 hospitalizations-a nationwide cohort study.

Nørgård Bente Mertz BM Zegers Floor Dijkstra FD Juhl Claus Bogh CB Kjeldsen Jens J Nielsen Jan J

Diabetic medicine : a journal of the British Diabetic Association 20221109 2

<h4>Aims</h4>This cohort study, based on Danish health registers, examined the post-acute consequences of hospitalization for COVID-19 in patients with diabetes.<h4>Methods</h4>The study population comprised all Danish citizens (≥18 years old) who had diabetes when the pandemic started. A patient was exposed if he/she had a hospitalization with COVID-19 after 1 March 2020. A patient was unexposed when he/she was not hospitalized with COVID-19 between 1 March 2020 and the end of follow-up (4 Janu ...[more]

PMID: 36271495

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Dataset Information

Diabetes mellitus and the risk of post-acute COVID-19 hospitalizations-a nationwide cohort study.

Aims

Methods

Results

Conclusions/interpretation

Publications

Diabetes mellitus and the risk of post-acute COVID-19 hospitalizations-a nationwide cohort study.

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