Systemic inflammation and menstrual cycle length in a prospective cohort study.

ABSTRACT:

Background

Local inflammation plays an important role in normal folliculogenesis and ovulation, and conditions of chronic systemic inflammation, such as obesity and polycystic ovarian syndrome, can disrupt normal follicular dynamics.

Objective

This study aimed to determine the association between systemic inflammation, as measured by C-reactive protein levels, and menstrual cycle length.

Study design

This study was a secondary analysis using data from Time to Conceive, a prospective time-to-pregnancy cohort study. The association between cycle length and C-reactive protein was analyzed using multivariable linear mixed and marginal models adjusted for age, race, education, body mass index, time since oral contraceptive use, alcohol, smoking, caffeine consumption, and e

SUBMITTER: Harris BS 

PROVIDER: S-EPMC9877159 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature