Evaluating an advanced double intravenous vasopressor automated system to treat hypotension during spinal anesthesia for cesarean delivery: a randomized controlled trial.

ABSTRACT:

Background

The optimal treatment of hypotension during spinal anaesthesia is uncertain. A novel double intravenous vasopressor automated (DIVA) system reduces hypotension compared to standard care, and was subsequently modified to an advanced-DIVA (ADIVA) system. The primary objective was to compare ADIVA versus DIVA on incidence of hypotension (systolic BP (SBP) < 80% baseline).

Methods

We conducted a randomized-controlled trial in women undergoing elective cesarean delivery under spinal anesthesia. SBP and heart rate were measured continuously using a Nexfin monitor. ADIVA delivered 25 μg phenylephrine (heart rate > 60 beats.min^-1) or 2 mg ephedrine (heart rate < 60 beats.min^-1) at SBP 90 to 110% of baseline, 50 μg phenylephrine or 4 mg ephedrine at S

SUBMITTER: Tan HS 

PROVIDER: S-EPMC9878794 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature