Neonatal Arterial Ischaemic Stroke: Advances in Pathologic Neural Death, Diagnosis, Treatment, and Prognosis.
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ABSTRACT:
SUBMITTER: He Y
PROVIDER: S-EPMC9890291 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
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Neonatal Arterial Ischaemic Stroke: Advances in Pathologic Neural Death, Diagnosis, Treatment, and Prognosis.
He Yang Y Ying Junjie J Tang Jun J Zhou Ruixi R Qu Haibo H Qu Yi Y Mu Dezhi D
Current neuropharmacology 20221101 12
Neonatal arterial ischaemic stroke (NAIS) is caused by focal arterial occlusion and often leads to severe neurological sequelae. Neural deaths after NAIS mainly include necrosis, apoptosis, necroptosis, autophagy, ferroptosis, and pyroptosis. These neural deaths are mainly caused by upstream stimulations, including excitotoxicity, oxidative stress, inflammation, and death receptor pathways. The current clinical approaches to managing NAIS mainly focus on supportive treatments, including seizure ...[more]
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