Novel insights into the somatic proteome of Strongyloides stercoralis infective third-stage larvae.

ABSTRACT:

Background

Strongyloidiasis is a neglected tropical disease affecting an estimated 600 million people, particularly in resource-limited settings. The infection can persist lifelong due to unusual auto-infective cycle of Strongyloides stercoralis. The lack of a diagnostic gold standard and limited knowledge of the mechanisms underpinning this chronic infection are key issues in disease management. To date, only a few proteomics studies have been conducted to elucidate the molecular mechanisms associated with Strongyloides parasitism or to highlight novel immunological markers, with the result that our knowledge of S. stercoralis proteome remains limited. This study aims at expanding the characterization of S. stercoralis infective larvae (iL3) in order to further explore the mechani

SUBMITTER: Dishnica K 

PROVIDER: S-EPMC9890704 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature