Impact of percutaneous coronary intervention of chronic total occlusions on absolute perfusion in remote myocardium.

ABSTRACT:

Background

Revascularisation of a chronic total coronary occlusion (CTO) impacts the coronary physiology of the remote myocardial territory.

Aims

This study aimed to evaluate the intrinsic effect of CTO percutaneous coronary intervention (PCI) on changes in absolute perfusion in remote myocardium.

Methods

A total of 164 patients who underwent serial [¹⁵O]H_²O positron emission tomography (PET) perfusion imaging at baseline and three months after successful single-vessel CTO PCI were included to evaluate changes in hyperaemic myocardial blood flow (hMBF) and coronary flow reserve (CFR) in the remote myocardium supplied by both non-target coronary arteries.

Results

Perfusion indices in CTO and remote myocardium showed a positive co

SUBMITTER: de Winter RW 

PROVIDER: S-EPMC9912974 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature