Dataset Information

Time of Day and Chronotype-Dependent Synchrony Effects Exercise-Induced Reduction in Migraine Load: A Pilot Cross-Over Randomized Trial.

ABSTRACT: Migraines are the most common cause of chronic pain. Effective, non-pharmacological strategies to reduce migraine load, like exercise, are needed, but it is unclear how exercise timing and chronotype modulate the effects. We sought to determine the effects of time-of-day of exercise, and synchrony with one's chronotype, on migraine load. We performed a pilot cross-over randomized trial where participants with chronic migraine completed two one-month exercise interventions, consisting of either morning exercise (before 09:00 a.m.) or evening exercise (after 7:00 p.m.) in a randomized repeated measures cross-over design (Clinical Trial #NCT04553445). Synchrony was determined by exercise time and chronotype (i.e., a morning type participant exercising in the morning is 'in-sync,' while an evening type participant exercising in the morning is 'out-of-sync'). Migraine burden, and anthropometric assessment occurred before and after each month of exercise. Data was analyzed using repeated measures ANOVA with significance accepted at p < 0.05. When comparing morning and evening exercise, there was no significant improvements in any migraine-related parameters. However, when comparing in-sync and out-of-sync exercise, we found that migraine burden was only improved following in-sync exercise, while no benefits were seen in out-of-sync exercise. Our data suggests that exercise timing has limited impact, but synchrony with chronotype may be essential to decrease migraine load in chronic migraineurs.

SUBMITTER: Malek EM

PROVIDER: S-EPMC9915413 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Time of Day and Chronotype-Dependent Synchrony Effects Exercise-Induced Reduction in Migraine Load: A Pilot Cross-Over Randomized Trial.

Malek Elias M EM Navalta James W JW McGinnis Graham R GR

International journal of environmental research and public health 20230123 3

Migraines are the most common cause of chronic pain. Effective, non-pharmacological strategies to reduce migraine load, like exercise, are needed, but it is unclear how exercise timing and chronotype modulate the effects. We sought to determine the effects of time-of-day of exercise, and synchrony with one's chronotype, on migraine load. We performed a pilot cross-over randomized trial where participants with chronic migraine completed two one-month exercise interventions, consisting of either m ...[more]

PMID: 36767448

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Dataset Information

Time of Day and Chronotype-Dependent Synchrony Effects Exercise-Induced Reduction in Migraine Load: A Pilot Cross-Over Randomized Trial.

Publications

Time of Day and Chronotype-Dependent Synchrony Effects Exercise-Induced Reduction in Migraine Load: A Pilot Cross-Over Randomized Trial.

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