Re-envisioning community genetics: community empowerment in preventive genomics.

ABSTRACT: As genomic technologies rapidly develop, polygenic scores (PGS) are entering into a growing conversation on how to improve precision in public health and prevent chronic disease. While the integration of PGS into public health and clinical services raises potential benefits, it also introduces potential harms. In particular, there is a high level of uncertainty about how to incorporate PGS into clinical settings in a manner that is equitable, just, and aligned with the long-term goals of many healthcare systems to support person-centered and value-based care. This paper argues that any conversation about whether and how to design and implement PGS clinical services requires dynamic engagement with local communities, patients, and families. These parties often face the consequences, both po

SUBMITTER: Wand H 

PROVIDER: S-EPMC9918397 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature