Organization and engagement of a prefrontal-olfactory network during olfactory selective attention.

ABSTRACT:

Background

Sensory perception is profoundly shaped by attention. Attending to an odor strongly regulates if and how it is perceived - yet the brain systems involved in this process are unknown. Here we report integration of the medial prefrontal cortex (mPFC), a collection of brain regions integral to attention, with the olfactory system in the context of selective attention to odors.

Methods

First, we used tracing methods to establish the tubular striatum (TuS, also known as the olfactory tubercle) as the primary olfactory region to receive direct mPFC input in rats. Next, we recorded (i) local field potentials from the olfactory bulb (OB), mPFC, and TuS, or (ii) sniffing, while rats completed an olfactory selective attention task.

Results

Gamma power and coupling of

SUBMITTER: Cansler HL 

PROVIDER: S-EPMC9930634 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature