The highest percentage of Gleason Pattern 4 is a predictor in intermediate-risk prostate cancer.

ABSTRACT:

Objectives

This study aims to clarify the clinicopathological significance of several novel pathological markers, including the percentage of Gleason pattern 4 and small/non-small cribriform pattern, in intermediate-risk Gleason score 3 + 4 = 7 prostate cancer.

Subjects and methods

Two-hundred and twenty-eight patients with Gleason score 3 + 4 = 7 intermediate-risk prostate cancer who underwent radical prostatectomy between 2009 and 2019 at our institute were selected. Preoperative clinicopathological characteristics, including serum prostate-specific antigen level, clinical T stage, percentage of cancer-positive cores at biopsy, small/non-small cribriform pattern, the highest percentage of Gleason pattern 4, the total length of Gleason pattern 4 and percentage of Gleason sc

SUBMITTER: Sato S 

PROVIDER: S-EPMC9931537 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature