Chromosome-length genome assembly of Teladorsagia circumcincta - a globally important helminth parasite in livestock.

ABSTRACT:

Background

Gastrointestinal (GIT) helminthiasis is a global problem that affects livestock health, especially in small ruminants. One of the major helminth parasites of sheep and goats, Teladorsagia circumcincta, infects the abomasum and causes production losses, reductions in weight gain, diarrhoea and, in some cases, death in young animals. Control strategies have relied heavily on the use of anthelmintic medication but, unfortunately, T. circumcincta has developed resistance, as have many helminths. Vaccination offers a sustainable and practical solution, but there is no commercially available vaccine to prevent Teladorsagiosis. The discovery of new strategies for controlling T. circumcincta, such as novel vaccine targets and drug candidates, would be greatly accelerated by the

SUBMITTER: Hassan SU 

PROVIDER: S-EPMC9933375 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature