Stress-Delta B-Type Natriuretic Peptide Does Not Exclude ACS in the ED.

ABSTRACT:

Background

There are many detectable changes in circulating biomarkers in the setting of myocardial ischemia. We hypothesize that there are associated changes in circulating B-type natriuretic peptide (BNP) level after stress-induced myocardial ischemia, which can be used for emergency department (ED) acute coronary syndrome (ACS) risk stratification.

Methods

In a prospective study, we enrolled 340 patients over the age of 30 receiving an exercise echocardiography stress test in an ED observational unit for suspected ACS. We collected blood samples at baseline and at 2 and 4 h post-stress test, measuring the relative and absolute changes (stress-delta) in plasma BNP concentrations. In addition, patients were contacted at 90 days and at 1 year posttest for a follow-up. We cal

SUBMITTER: Susman SJ 

PROVIDER: S-EPMC9939016 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature