Determinants and Prognostic Implications of Hepatorenal Dysfunction in Adults With Congenital Heart Disease.

ABSTRACT:

Background

There are limited data on the prognostic role of hepatorenal function indices in ambulatory patients with congenital heart disease (CHD). The purpose of this study was to determine the prevalence, risk factors, and prognostic implications of hepatorenal dysfunction, as measured by Model for End-Stage Liver Disease Excluding International Normalised Ratio (MELD-XI) score, in adults with CHD.

Methods

In this retrospective study of CHD patients with comprehensive metabolic panels (2003-2019), mild/moderate and severe hepatorenal dysfunction was defined as MELD-XI 11-15 and > 15, respectively.

Results

Of 4977 patients, 1376 (28%) had hepatorenal dysfunction (mild/moderate: n = 935 [19%]; severe: n = 441 [9%]). Hepatorenal dysfunction was most common in Fontan/u

SUBMITTER: Egbe AC 

PROVIDER: S-EPMC9940666 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature