Site-Selective Electrochemical Oxidation of Glycosides.

ABSTRACT: Quinuclidine-mediated electrochemical oxidation of glycopyranosides provides C3-ketosaccharides with high selectivity and good yields. The method is a versatile alternative to Pd-catalyzed or photochemical oxidation and is complementary to the 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO)-mediated C6-selective oxidation. Contrary to the electrochemical oxidation of methylene and methine groups, the reaction proceeds without oxygen.

SUBMITTER: Kidonakis M 

PROVIDER: S-EPMC9942207 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature